High Purity Anticoagulants platelet glycoprotein B Eptifibatide Powder CAS:188627-80-7
Description:
Eptifibatide is a platelet glycoprotein b/a receptor reversible antagonist,adverse reactions are mild , it can be discontinued immediately while adverse reactions occur . It has Strong effect and high selectivity . It has no antigenicity,and it does not cause allergic reactions. It is used For acute coronary syndrome, coronary intervention before treatment and acute Q-wave myocardial infarction. It can relieve unstable angina symptoms and reduce the incidence of cardiovascular events. It can limit the non-Q-wave myocardial infarction,and reduce through wall myocardial infarction occurrance.
Application:
Etibatide is a glycoprotein (GP) IIb/IIIa receptor (platelet factor I receptor) antagonist. By selectively and reversibly inhibiting the final common pathway of platelet aggregation (plasma coagulation factor I binds to GPIIb/IIIa), the ischemic state due to thrombosis can be reversed.
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
The drug should exclusively be used in hospitalized patients both because of the serious degree of patients' illness and because of the possible side-effects of eptifibatide.
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Packing:
Q&A
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
Q4: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q5: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer.
In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.
Detailed Product Information
Product Name : Eptifibatide
Trade Name: integrilin
CAS No.:188627-80-7
Molecular Formula: C35H49N11O9S2
Molecular Weight:831.96g/mol
Purity : 98% HPLC
Appearance: Lyophilized Powder
Typical use:Anticoagulants
Shelf Life :2 years
Payment Terms:T/T, Western Union, Money Gram
Storage:Refrigeration keep dry and away from light.
Product Name : Eptifibatide
Trade Name: integrilin
CAS No.:188627-80-7
Molecular Formula: C35H49N11O9S2
Molecular Weight:831.96g/mol
Purity : 98% HPLC
Appearance: Lyophilized Powder
Typical use:Anticoagulants
Shelf Life :2 years
Payment Terms:T/T, Western Union, Money Gram
Storage:Refrigeration keep dry and away from light.
Description:
Eptifibatide is a platelet glycoprotein b/a receptor reversible antagonist,adverse reactions are mild , it can be discontinued immediately while adverse reactions occur . It has Strong effect and high selectivity . It has no antigenicity,and it does not cause allergic reactions. It is used For acute coronary syndrome, coronary intervention before treatment and acute Q-wave myocardial infarction. It can relieve unstable angina symptoms and reduce the incidence of cardiovascular events. It can limit the non-Q-wave myocardial infarction,and reduce through wall myocardial infarction occurrance.
Application:
Etibatide is a glycoprotein (GP) IIb/IIIa receptor (platelet factor I receptor) antagonist. By selectively and reversibly inhibiting the final common pathway of platelet aggregation (plasma coagulation factor I binds to GPIIb/IIIa), the ischemic state due to thrombosis can be reversed.
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
The drug should exclusively be used in hospitalized patients both because of the serious degree of patients' illness and because of the possible side-effects of eptifibatide.
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| Item | Standard | Test Results |
| Identification | A.H-NMR:Comply with the structure | Complies |
| B.LC-MS:Comply with the structure | Complies | |
| C.The IR spectrum of sample should be identical with that of reference standard; | Complies | |
| D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. | Complies | |
| Crystallinity | meets the requirements. | Complies |
| Loss on drying | ≤2.0% | 0.19% |
| Heavy metals | ≤10 ppm | <10ppm |
| Water | ≤1.0% | 0.1% |
| Sulphated ash | ≤0.5%, determined on 1.0 g. | 0.009% |
| Related substances | Unspecified impurities: for each impurity | <0.10% |
| Total Impurity | 0.18% | |
| Purity | ≥99.0% | 99.7% |
| Assay | 99.0%~101.0% (anhydrous substance). | 99.8% |
| Microbiological Analysis | ||
| Total plate count | ≤1000cfu/g | Complies |
| Yeast and Moulds | ≤100cfu/g | Complies |
| E. Coli. | Absent | Negative |
| Salmonella | Absent | Negative |
| S.aureus | Absent | Negative |
| Storage | Preserve in well-closed, light-resistant and airtight containers. | Complies |
Packing:
- Delivery Time: Around 3-5 workdays after your payment.
- Package: In fiber-drums with two-plastic bags inside.
- Net Weight: 25kgs/Drum / Gross Weight: 28kgs/Drum
- Drum Size & Volume: I.D.42cm × H52cm, 0.08 m³/ Drum
- Storage: Stored in dry and cool place, keep away from strong light and heat.
- Shelf Life: Two years when properly stored.
- 1, DHL Express, FEDEX and EMS for quantity less than 50KG, usually called as DDU service;
- 2, Sea shipping for quantity over 500KG; and air shipping is available for 50KG above;
- 3, For high value products, please select air shipping and DHL express for safe;
- 4, Please confirm if you can make the clearance when goods reach your customs before placing an order, for buyers from Mexico, Turkey, Italy, Romania,Russia, and other remote area.
Q&A
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
Q4: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q5: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer.
In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.
